Validation of Antibody Specificity Using Knockdown or Knockout Techniques

It is often assumed that antibodies sold by reputable, commercial vendors are specific to the protein of interest. However, the majority of research antibodies in the market have not been tested for specificity, which can waste time, money, and have the potential to generate unfounded results. To ensure our antibodies are specific, we validate all of our antibodies using knockdown or knockout techniques. Only those that are deemed to be specific by detecting the protein of interest in control cell lysates but not in mutant cell lysates are marketed and sold by GenuIN.