Human Nasopharyngeal Swab Lysate #VCS1
Lysed NP Swab Specimen
Disclaimer: For research use only.
Specimen Type: Nasopharyngeal swab specimens with no patient identification
Original Medium: Saline
Verification Method: Positives and negatives were confirmed by EUA qRT-PCR
Product forms: Lysed in either non-denatured or denatured buffer (upon request)
Biosafety Level: BSL1
Volume: 1 mL
Validated Applications: Western blotting; ELISA
Shipping: Dry ice (non-denatured lysates) or ice pad (denatured lysates)
Storage Condition: < -20°C for both non-denatured and denatured lysates, stable for 1 year after receipt. Avoid repeated freeze-thaw cycles.
The virial load of SARS-CoV-2 coronaviruses in different types of clinical specimens can vary dramatically. In general, lower respiratory tract specimens have more viral load than those from the upper respiratory tract (Hu et al., 2020; Wang et al., 2020). A recent study shows that bronchoalveolar lavage fluid specimens contain the highest vial load, followed by sputum, nasal swabs, fibrobronchoscope brush biopsy, pharyngeal swabs, feces, and blood (Wang et al., 2020). As a commonly used procedure for COBID-19 diagnosis, nasopharyngeal (NP) swabs are used to collect specimens from the surface of the respiratory mucosa (Marty et al., 2020). NP swab specimens are valuable materials to study SARS-CoV-2 viruses and the mucosal immune responses triggered by SARS-CoV-2.
Hu, B., Guo, H., Zhou, P., and Shi, Z.L. (2020). Characteristics of SARS-CoV-2 and COVID-19. Nat Rev Microbiol.
Marty, F.M., Chen, K., and Verrill, K.A. (2020). How to Obtain a Nasopharyngeal Swab Specimen. N Engl J Med 382, e76.
Wang, W., Xu, Y., Gao, R., Lu, R., Han, K., Wu, G., and Tan, W. (2020). Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA 323, 1843-1844.