Cell Cycle Regulation
The cell cycle, also known as the cell-division cycle, refers to a series of orderly events or a cycle of stages that cells pass through to divide into two daughter cells. In normal physiological environments, the cell cycle is tightly regulated to maintain tissue homeostasis and body health; however, in the pathogenesis of major disorders such as cancer, neurodegenerative disease, inflammation, infection, stroke, and cardiovascular diseases, cell cycle is dysregulated, resulting in either uncontrolled cell growth or irreversible cell death. The study of a complex network of biochemical pathways that regulate cell cycle checkpoints, DNA damage and repair, apoptosis, autophagy, and necrosis will help us understand this life-and-death process and develop new therapeutic approaches to treat these debilitating diseases. At Genuine Biotech, we provide high-quality antibodies and knockdown validated lentiviral shRNAs to help you investigate the biochemical mechanisms of cell cycle.
Cell Cycle Phase Transition
Protein Name | Item name | Catalog No. | Reactivity | Applications |
---|---|---|---|---|
KD-Validated Ajuba LIM Protein Rabbit mAb | 1411 | Human | WB | |
KD-Validated Aurora Kinase A Rabbit mAb | 1761 | Human | WB, IC | |
Cyclin A2 Rabbit mAb | 61152 | Human, Mouse | WB, IHC | |
KD-Validated Cyclin D1 Rabbit mAb | 81151 | Human, Mouse, Rat | WB | |
KD-Validated Cyclin D1 Rabbit mAb | 1151 | Human, mouse, rat | WB | |
KD-Validated Cyclin D2 Rabbit mAb | 1152 | Human, mouse, rat | WB | |
KD-Validated Cyclin Dependent Kinase 2 Rabbit mAb | 4124 | Human, mouse, rat, cow, dog, chicken, pig | WB | |
KD-Validated Cyclin Dependent Kinase 4 Rabbit mAb | 81244 | Human, Mouse, Rat | WB | |
KD-Validated Cyclin Dependent Kinase 4 Rabbit mAb | 1244 | Human, mouse, cow, dog, pig | WB, IC, F | |
KD-Validated Cyclin Dependent Kinase Inhibitor 1B Rabbit mAb | 1241 | Human, mouse, rat | WB | |
KD-Validated Cyclin Dependent Kinase Inhibitor 1B Rabbit mAb | 81241 | Human | WB | |
KD-Validated Cullin 4A Rabbit mAb | 81744 | Human, dog, chicken | WB, IHC | |
KD-Validated Eukaryotic Translation Initiation Factor 4E Binding Protein 1 ... | 2361 | Human, mouse, rat | WB, IC, F | |
KD-Validated Minichromosome Maintenance Complex Component 7 Rabbit mAb | 5157 | Human, mouse, rat, cow, dog, pig | WB, IC | |
KD-Validated Proliferating Cell Nuclear Antigen Rabbit mAb | 6151 | Human, mouse, rat, cow, dog, chicken, pig | WB, IC, F | |
KD-Validated Protein Phosphatase 2 Scaffold Subunit Aalpha Rabbit mAb | 6621 | Human, mouse, rat, cow, dog, pig | WB | |
KD-Validated Protein Kinase CAMP-Activated Catalytic Subunit Alpha Protein ... | 6611 | Human, mouse, rat | WB | |
7710 | Beta-Tubulin Mouse mAb | Human, mouse, rat, cow, dog, chicken, pig | WB | |
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamm... | 69833 | Human, mouse | WB |