Embryonic Stem Cells

Neurodegenerative Diseases

 
 
 
 

The progressive death of neurons and other brain cells will cause cognitive and/or motor deterioration, collectively known as neurodegenerative disorders or diseases. Among all neurodegenerative diseases, Alzheimer’s disease, Parkinson’s disease, and Huntington’s diseases are the most severe, because these diseases are incurable and debilitating, with Alzheimer’s affecting memory, whereas the other two weaken movement. Since neurodegenerative diseases have a massive impact on the quality of life and lifespan of older people, an understanding of the pathophysiology of these conditions will facilitate the development of targeted therapies. At Genuine Biotech, we provide high-quality antibodies and knockdown validated lentiviral shRNAs to help you investigate the biochemical mechanisms of neurodegenerative diseases.

Alzheimer Disease-presenilin Pathway

Protein Name
Item name
Catalog No.
Reactivity
Applications
KD-Validated Dishevelled Segment Polarity Protein 3 Rabbit mAb
2843
Human, mouse, rat
WB
Furin, Paired Basic Amino Acid Cleaving Enzyme Rabbit mAb
62765
Human, mouse
WB, IHC, IC
Lysine Acetyltransferase 7 Rabbit mAb
64177
Human, mouse, rat
WB
Matrix Metallopeptidase 13 Rabbit mAb
65563
Human
WB, IHC
Matrix Metallopeptidase 9 Rabbit mAb
65569
Human, mouse, rat, pig
WB, IHC
KD-Validated Nicastrin Rabbit mAb
5175
Human
IC
KD-Validated Notch Receptor 2 Rabbit mAb
5571
Human, mouse, rat
IC
Wnt Family Member 5A Rabbit mAb
68571
Human
WB, IHC
Actin Alpha 2, Smooth Muscle Rabbit mAb
61172
Human
WB, IHC
KD-Validated Beta-actin Rabbit mAb
1171
Human, mouse, rat
WB, IC, F
Beta-Actin Mouse mAb
1170
Human, mouse, rat, cow, dog, chicken, pig
WB
Beta-Actin Rabbit mAb
9171
Human, mouse, rat, cow, dog, chicken, pig
WB
KD-Validated ADAM Metallopeptidase Domain 17 Rabbit mAb
1217
Human
WB
Cadherin 1 Rabbit mAb
61231
Human
WB
KD-Validated Catenin Beta 1 Rabbit mAb
1711
Human, mouse, rat
WB, IC, F

Alzheimer Disease-amyloid Secretase Pathway

Protein Name
Item name
Catalog No.
Reactivity
Applications
KD-Validated ADAM Metallopeptidase Domain 17 Rabbit mAb
1217
Human
WB
KD-Validated ADAM Metallopeptidase Domain 9 Rabbit mAb
1259
Human, mouse, rat
WB
Furin, Paired Basic Amino Acid Cleaving Enzyme Rabbit mAb
62765
Human, mouse
WB, IHC, IC
Mitogen-Activated Protein Kinase 3 Rabbit mAb
65164
Human, mouse
WB, IHC
Mitogen-Activated Protein Kinase 8 Rabbit mAb
65168
Human
WB
KD-Validated Nicastrin Rabbit mAb
5175
Human
IC
KD-Validated Protein Kinase CAMP-Activated Catalytic Subunit Alpha Protein ...
6611
Human, mouse, rat
WB
KD-Validated Protein Kinase C Alpha Rabbit mAb
6411
Human
IC

Parkinson Disease

Protein Name
Item name
Catalog No.
Reactivity
Applications
Heat Shock Protein Family A (Hsp70) Member 5 Mouse mAb
63765
Human
WB
Mitogen-Activated Protein Kinase 3 Rabbit mAb
65164
Human, mouse
WB, IHC
Mitogen-Activated Protein Kinase 8 Rabbit mAb
65168
Human
WB
KD-Validated SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase Rabbit mAb
7610
Human, mouse, rat
WB, IC, F
Ubiquitin C-Terminal Hydrolase L1 Rabbit mAb
67131
Human
WB
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta...
69831
Human, mouse, rat
WB, IHC
Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamm...
69833
Human, mouse
WB

Huntington Disease

Protein Name
Item name
Catalog No.
Reactivity
Applications
Actin Alpha 2, Smooth Muscle Rabbit mAb
61172
Human
WB, IHC
KD-Validated Beta-actin Rabbit mAb
1171
Human, mouse, rat
WB, IC, F
Beta-Actin Mouse mAb
1170
Human, mouse, rat, cow, dog, chicken, pig
WB
Beta-Actin Rabbit mAb
9171
Human, mouse, rat, cow, dog, chicken, pig
WB
KD-Validated AKT Serine/Threonine Kinase 2 Rabbit mAb
1472
Human, mouse, rat
WB
KD-Validated Caspase 3 Rabbit mAb
1173
Human, mouse, rat, cow, dog, pig
WB
KD-Validated Caspase 3 Rabbit mAb
81173
Human
WB
KD-Validated Cell Division Cycle 42 Rabbit mAb
81214
Human, mouse, rat, cow, dog, chicken, pig
WB, IHC
FosB Proto-Oncogene, AP-1 Transcription Factor Subunit Rabbit mAb
62571
Human, mouse, rat
WB, IHC
KD-Validated Jun Proto-Oncogene Rabbit mAb
4750
Human, mouse, rat
WB
GAPDH Rabbit mAb
3199
Human, mouse, rat,Êcow, chicken, pig
WB
GAPDH Mouse mAb
3130
Human,Êmouse,Êrat,Êdog, chicken, pig
WB
Beta-Tubulin Mouse mAb
7710
Human, mouse, rat, cow, dog, chicken, pig
WB